Polynucleotides
Aesthetic Treatments
Heal. Strengthen. Rebuild, from within.
Polynucleotides are a new generation of injectable treatments designed to help your skin repair itself from the inside out.
Unlike traditional fillers or boosters, polynucleotides don’t just hydrate or add volume. Instead, they work at a cellular level, stimulating collagen, improving elasticity, calming inflammation, and encouraging your skin to regenerate and rebuild over time.
At Treeline Aesthetics, we offer polynucleotide treatments for clients looking to target early signs of ageing, sensitivity, or weakened skin without overloading it. Think of it as skin reset, slow, steady, and genuinely strengthening.
What Polynucleotides Can Help With
- Early signs of skin ageing
- Fine lines and thinning skin
- Puffiness or under-eye hollows
- Redness, inflammation or rosacea-prone skin
- Post-treatment recovery or skin barrier repair
- Loss of firmness or elasticity
- Scarring (including acne scars)
Common treatment areas:
- Under-eyes
- Cheeks
- Neck
- Décolletage
- Hands
Areas with previous skin trauma or scarring
How It Works
Polynucleotides are biostimulators, injectable molecules derived from purified DNA fragments that act as messengers to your skin cells.
They encourage fibroblasts to produce more collagen, improve blood flow to the skin, and promote long-term tissue repair. The result is skin that looks stronger, feels firmer, and behaves better, without being forced or filled.
Our Approach
Polynucleotides are ideal for clients who want natural improvements in their skin quality without looking like they’ve had ‘work done.’
We’ll talk you through how it works, what to expect, and whether this treatment is right for you — especially if you’ve tried other treatments in the past and want something more regenerative.
What to Expect
- Appointment time: Around 30 – 45 minutes
- Discomfort: Mild (numbing available if needed)
- Downtime: Possible redness, swelling, or light bruising for 24 – 48 hours
- Treatment Plan: Usually 2 – 3 sessions spaced 3 – 4 weeks apart
- Results: Gradual, building over 4 – 8 weeks
- Maintenance: Every 6 months (varies by skin type)
Aftercare Advice
- Avoid touching or applying pressure to the area for 6 hours
- No makeup for 24 hours
- Avoid alcohol, intense exercise, or heat exposure for 48 hours
- Keep the skin hydrated and use gentle skincare for the first few days
- We’ll provide you with personalised guidance based on the treatment area
Other Services
Frequently Asked Questions About Polynucleotides
No. They don’t add volume or act as hydrating agents. Instead, they stimulate your skin’s natural healing processes to improve long-term structure and texture.
You may notice subtle changes after a few weeks, but the most significant improvements usually appear after a full course, around 6 - 8 weeks in.
Yes, polynucleotides are particularly effective and gentle for under-eye concerns like puffiness, fine lines, or early hollowness.
Yes. In fact, it’s often recommended for sensitive or reactive skin, especially when other treatments feel too harsh. It also helps calm inflammation over time.
Yes. It works well alongside microneedling, skin boosters, or anti-wrinkle injections. We’ll guide you on the best timing and combinations for your skin.
Curious if Polynucleotides Are Right for You?
They’re ideal for skin that’s lost a bit of resilience, whether from aging, stress, or previous damage. We’ll help you decide if it’s the right approach for what you want to achieve.